The server or gateway invokes the application callable once for each request it receives from an HTTP client, that is directed at the application.
Currently wrappers are available for FastCGI, CGI, SCGI, AJP (using flup), twisted.web, Apache (using mod_wsgi or mod_python), Nginx (using mod_wsgi), and Microsoft IIS (using WFastCGI, isapi-wsgi, PyISAPIe, or an ASP gateway).
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